Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal genomics in Southern Zambia shows rising prevalence of Plasmodium falciparum mutations linked to delayed clearance after artemisinin-lumefantrine treatment.

Scientific reports - 5 Nov 2024

Fola Abebe A, Kobayashi Tamaki, Hamapumbu Harry, Musonda Michael, Katowa Ben, Matoba Japhet, Stevenson Jennifer C, Norris Douglas E, Thuma Philip E, Wesolowski Amy, Moss William J, Juliano Jonathan J, Bailey Jeffrey A

Abstract excerpt

The emergence of antimalarial drug resistance is an impediment to malaria control and elimination in Africa. Analysis of temporal trends in molecular markers of resistance is critical to inform policy makers and guide malaria treatment guidelines. In a low and seasonal transmission region of southern Zambia, we successfully genotyped 85.5% (389/455) of Plasmodium falciparum samples collected between 2013 and 2018...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimalarials
Share to Artemisinins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Drug Resistance

Share to Genomics

Share to Malaria, Falciparum

Share to Plasmodium falciparum

Share to Prevalence

Share to Zambia

Source

Open in PubMed Open full text

Identifiers

PMID: 39500918
DOI: 10.1038/s41598-024-76442-6
PMCID: PMC11538544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal genomics in Southern Zambia shows rising prevalence of Plasmodium falciparum mutations linked to delayed clearance after artemisinin-lumefantrine treatment.PMID 39500918Read ↗

Plasmodium falciparum Genomic Surveillance Reveals a Diversity of Kelch 13 Mutations in ZambiaSemantic proximity Read ↗

<i>Plasmodium falciparum</i> genomic surveillance reveals a diversity of <i>kelch13</i> mutations in ZambiaSemantic proximity Read ↗

Geographical Variation in Antimalarial Drug Resistance Marker Prevalence Across the Southern African Elimination Eight RegionSemantic proximity Read ↗

Emergence and Rising Prevalence of Artemisinin Partial Resistance Marker Kelch13 P441L in a Low Malaria Transmission Setting in Southern Zambia.Semantic proximity Read ↗

Surveillance of molecular markers for antimalarial resistance in Zambia: Polymorphism of Pfkelch 13, Pfmdr1 and Pfdhfr/Pfdhps genesSemantic proximity Read ↗

Temporal and spatial analysis of Plasmodium falciparum genomics reveals patterns of parasite connectivity in a low-transmission district in Southern Province, ZambiaSemantic proximity Read ↗

Emergence and Spread of Artemisinin-Resistant Malaria in ZambiaSemantic proximity Read ↗

Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of Plasmodium falciparum in Mozambique: protocolSemantic proximity Read ↗

Artemisinin Partial Resistance Mutations in Zanzibar and Tanzania Suggest Regional Spread and African Origins, 2023.Semantic proximity Read ↗

Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in ZambiaSemantic proximity Read ↗

Clonal Transmission of Emerging Novel <i>Plasmodium falciparum</i> Kelch13 Mutations and Increasing Complexity of Infection in Libreville, Gabon, 2021-2023Semantic proximity Read ↗

Understanding the Global Spread of Artemisinin Resistance: Insights from over 100K <i>Plasmodium falciparum</i> SamplesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.