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ZNF652 exerts a tumor suppressor role in lung cancer by transcriptionally downregulating cyclin D3

5 Nov 2024

Abstract excerpt

Dysfunction of zinc finger protein 652 (ZNF652) is associated with various malignant tumors. However, the role of ZNF652 in lung cancer (LC) is poorly understood. Here, we identified that ZNF652 was downregulated in human LC tissues and cell lines. Low ZNF652 expression was associated with poor survival in LC patients. Overexpression of ZNF652 inhibited cell viability, proliferation, migration, and invasion of LC...

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PMID: 39500884
DOI: 10.1038/s41419-024-07197-1

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