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Article

Gastroesophageal reflux disease, mood swings, and frozen shoulder: A two-sample, two-step Mendelian randomization study.

Medicine - 1 Nov 2024

Guo Qiu-Cheng, Cai He, Hong Wu, Chen Yin-Ying, Lu Qing, Zheng Shu-Guang

Abstract excerpt

A Mendelian randomization (MR) study was undertaken to establish a causal link between gastroesophageal reflux disease (GERD) and frozen shoulder (FS), examining whether the risk of GERD with FS is mediated through mood fluctuations. Genetic loci from populations of independent European ancestry were selected as instrumental variables for GERD, FS, and mood swings. The primary analysis employed the...

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Gastroesophageal Reflux
Mendelian Randomization Analysis
Polymorphism, Single Nucleotide
Risk Factors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39495976
DOI: 10.1097/MD.0000000000040301
PMCID: PMC11537667

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