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Article

Transcriptomic imputation identifies tissue-specific genes associated with cervical myelopathy.

The spine journal : official journal of the North American Spine Society - 1 Mar 2025

Seah Carina, Karabacak Mert, Margetis Konstantinos

Abstract excerpt

BACKGROUND CONTEXT: Degenerative cervical myelopathy (DCM) is a progressive spinal condition that can lead to severe neurological dysfunction. Despite its degenerative pathophysiology, family history has shown to be a largely important factor in incidence and progression, suggesting that inherent genetic predisposition may play a role in pathophysiology. PURPOSE: To determine the tissue-specific, functional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39491753
DOI: 10.1016/j.spinee.2024.10.014

Genes

BDH2
C1RL
CDK5
CLEC4D
HES6
KLHL29
PAFAH1B2
PI16
PTPRG
RCSD1
SPATA1
TMEM183A
USP43

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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