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Article

Epistatic effects of IGHG and FCGRIIB genes on the development of Alzheimer's disease in African Americans.

Immunogenetics - 4 Nov 2024

Pandey Janardan P, Nietert Paul J, Namboodiri Aryan M, Bennett David A, Barnes Lisa L

Abstract excerpt

Genome-wide association studies (GWAS) of Alzheimer's disease (AD) have identified a large number of susceptibility genes, but most of AD heritability remains unexplained, implying the existence of additional genes. Furthermore, the majority of the GWAS have been conducted in people of European descent, and the genes important for AD susceptibility in people of African descent have been underexplored. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39489839
DOI: 10.1007/s00251-024-01358-4
PMCID: PMC11532319

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