Article
Chronic obstructive pulmonary disease.
Comprehensive Physiology - 1 Jan 2014
Brusasco Vito, Martinez Fernando
Abstract excerpt
COPD is characterized by airflow limitation that is not fully reversible. The morphological basis for airflow obstruction results from a varying combination of obstructive changes in peripheral conducting airways and destructive changes in respiratory bronchioles, alveolar ducts, and alveoli. A reduction of vascularity within the alveolar septa has been reported in emphysema. Typical physiological changes reflect...
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