Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Severity grading of chronic obstructive pulmonary disease: the confounding effect of phenotype and thoracic gas compression.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Apr 2015

Pellegrino Riccardo, Crimi Emanuele, Gobbi Alessandro, Torchio Roberto, Antonelli Andrea, Gulotta Carlo, Baroffio Michele, Papa Giuseppe Francesco Sferrazza, Dellacà Raffaele, Brusasco Vito

Abstract excerpt

Current guidelines recommend severity of chronic obstructive pulmonary disease be graded by using forced expiratory volume in 1 s (FEV1). But this measurement is biased by thoracic gas compression depending on lung volume and airflow resistance. The aim of this study was to test the hypothesis that the effect of thoracic gas compression on FEV1 is greater in emphysema than chronic bronchitis because of larger...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Artifacts
Share to Diagnosis, Computer-Assisted

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pulmonary Disease, Chronic Obstructive

Share to Reproducibility of Results

Share to Respiratory Function Tests

Share to Sensitivity and Specificity

Share to Severity of Illness Index

Source

Identifiers

PMID: 25414244
DOI: 10.1152/japplphysiol.00801.2014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Severity grading of chronic obstructive pulmonary disease: the confounding effect of phenotype and thoracic gas compression.PMID 25414244Read ↗

Characterisation of phenotypes based on severity of emphysema in chronic obstructive pulmonary disease.Semantic proximity Read ↗

Chronic obstructive pulmonary disease.Semantic proximity Read ↗

Predominant emphysema phenotype in chronic obstructive pulmonary.Semantic proximity Read ↗

Quantitative Chest Computed Tomography in Chronic Obstructive Pulmonary Disease: Assessing the Role of Emphysema Severity and its Correlation with Clinical Characteristics, Lung Function, and Plasma Levels of VEGF and IL-1βSemantic proximity Read ↗

Phenotyping COPD Patients with Emphysema Distribution Using Quantitative CT Measurement; More Severe Airway Involvement in Lower Dominant Emphysema.Semantic proximity Read ↗

Identification of Chronic Obstructive Pulmonary Disease Axes That Predict All-Cause Mortality: The COPDGene Study.Semantic proximity Read ↗

[Complexity in chronic obstructive pulmonary disease. Individualized treatment, new approaches, phenotypes and comorbidities].Semantic proximity Read ↗

Emphysema- and airway-dominant COPD phenotypes defined by standardised quantitative computed tomography.Semantic proximity Read ↗

Defining a phenotype of severe COPD patients who develop chronic hypercapnia.Semantic proximity Read ↗

Sensitivity and specificity of various lung function parameters recommended for phenotyping COPD in clinical practice.Semantic proximity Read ↗

Subtyping COPD by Using Visual and Quantitative CT Imaging Features.Semantic proximity Read ↗

Prevalence of comorbidities according to predominant phenotype and severity of chronic obstructive pulmonary disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.