Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma metabolites as mediators in the relationship between inflammation-related proteins and benign prostatic hyperplasia: insights from mendelian randomization.

Scientific reports - 30 Oct 2024

Cui Yan, Wang Hui, Wang Yuting

Abstract excerpt

Benign prostatic hyperplasia (BPH) is a condition commonly observed in aging males. Inflammatory and metabolic factors are pivotal in the development and progression of BPH. The degree to which the effects of 91 inflammation-related proteins on BPH are mediated by 1400 plasma metabolites remains ambiguous. Our research analyzed the impact of these traits utilizing genetic evidence.Two-sample Mendelian...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Inflammation
Share to Interleukin-2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lysine

Share to Mendelian Randomization Analysis

Share to Polymorphism, Single Nucleotide

Share to Prostatic Hyperplasia

Source

Open in PubMed Open full text

Identifiers

PMID: 39478098
DOI: 10.1038/s41598-024-77515-2
PMCID: PMC11525667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 19 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma metabolites as mediators in the relationship between inflammation-related proteins and benign prostatic hyperplasia: insights from mendelian randomization.PMID 39478098Read ↗

Plasma metabolites as mediators in inflammation-related proteins - benign prostatic hyperplasia risk: insights from Mendelian randomizationSemantic proximity Read ↗

A genetic study to identify pathogenic mechanisms and drug targets for benign prostatic hyperplasia: a multi-omics Mendelian randomization study.Semantic proximity Read ↗

Association between circulating inflammatory proteins and benign prostatic disease: a Mendelian randomization study.Semantic proximity Read ↗

Correlation between benign prostatic hyperplasia and comorbidities: a systematic analysis integrating global burden of disease and mendelian randomization studySemantic proximity Read ↗

Causal relationship between prostatic diseases and prostate cancer: a mendelian randomization study.Semantic proximity Read ↗

The causal effect of metabolic syndrome and its components on benign prostatic hyperplasia: A univariable and multivariable Mendelian randomization study.Semantic proximity Read ↗

Uncovering metabolite-immune interactions in the pathogenesis of psoriatic arthritis: A 2-sample Mendelian randomization study.Semantic proximity Read ↗

Prostatitis, benign prostatic hyperplasia, and prostate cancer: a bidirectional Mendelian randomization study and clinical implications for these patients' populations.Semantic proximity Read ↗

Mediation effect of plasma metabolites on the relationship between immune cells and the risk of prostatitis: A study by bidirectional 2-sample and Bayesian-weighted Mendelian randomization.Semantic proximity Read ↗

Causal links of human serum metabolites on the risk of prostate cancer: insights from genome-wide Mendelian randomization, single-cell RNA sequencing, and metabolic pathway analysis.Semantic proximity Read ↗

Causal relationship between obesity, lifestyle factors and risk of benign prostatic hyperplasia: a univariable and multivariable Mendelian randomization study.Semantic proximity Read ↗

SLC25A37 is casually associated with the increased incidence of benign prostatic hyperplasiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.