Causal effect of gut microbiota on juvenile idiopathic arthritis: A two-sample Mendelian a randomization study.

Abstract excerpt

There is increasing evidence of a significant association between the gut microbiome and juvenile idiopathic arthritis (JIA). However, whether this association is causal remains to be determined. This study was a two-sample Mendelian randomization (MR) study using publicly available genome-wide association study (GWAS) summary data to investigate the causal relationship between the gut microbiome and JIA. We used...

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• Arthritis, Juvenile
• Bacteria
• Gastrointestinal Microbiome
• Genome-Wide Association Study
• Mendelian Randomization Analysis