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Article

Causal Relationship Between Gut Microbiota and Autoimmune Diseases: A Two-Sample Mendelian Randomization Study.

Frontiers in immunology - 1 Jan 2021

Xu Qian, Ni Jing-Jing, Han Bai-Xue, Yan Shan-Shan, Wei Xin-Tong, Feng Gui-Juan, Zhang Hong, Zhang Lei, Li Bin, Pei Yu-Fang

Abstract excerpt

Background: Growing evidence has shown that alterations in gut microbiota composition are associated with multiple autoimmune diseases (ADs). However, it is unclear whether these associations reflect a causal relationship. Objective: To reveal the causal association between gut microbiota and AD, we conducted a two-sample Mendelian randomization (MR) analysis. Materials and Methods: We assessed genome-wide...

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Source

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Identifiers

PMID: 35140703
DOI: 10.3389/fimmu.2021.746998
PMCID: PMC8819003

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