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Article

Emerging integrase resistance in an international perinatal virtual clinic.

AIDS (London, England) - 1 Mar 2025

Eni-Olotu Ayolola, Mackie Nicola E, Glenn Jessica, Bailey Angela, Bamford Alasdair, Kenny Julia, Levin Leon, Lyall Hermione, Milheiro Silva Tiago, Simon Katie, Tickner Neil, Turkova Anna, Welch Steven, Foster Caroline

Abstract excerpt

OBJECTIVE: The aim of this study was to identify the prevalence of emergent integrase drug resistance mutations (INSTI-DRMs) in international referrals to a perinatal virtual clinic (PVC). DESIGN: A retrospective cohort study. SETTING: Monthly multidisciplinary PVC reviewing complex case management for children and adolescents with perinatally acquired HIV (CAWHIV). PARTICIPANTS: One hundred fourteen cases...

Read the complete abstract on PubMed

Topics

Humans
HIV Infections
Retrospective Studies
Female
Male
Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Adolescent

Child

HIV Integrase Inhibitors

Viral Load

HIV Integrase

HIV-1

Mutation

Pyridones

CD4 Lymphocyte Count

Source

Identifiers

PMID: 39469738
DOI: 10.1097/QAD.0000000000004048

Genes

CD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

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