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Metabolic modelling as a powerful tool to identify critical components of Pneumocystis growth medium

28 Oct 2024

Abstract excerpt

Establishing suitable in vitro culture conditions for microorganisms is crucial for dissecting their biology and empowering potential applications. However, a significant number of bacterial and fungal species, including Pneumocystis jirovecii, remain unculturable, hampering research efforts. P. jirovecii is a deadly pathogen of humans that causes life-threatening pneumonia in immunocompromised individuals and...

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PMID: 39466836
DOI: 10.1371/journal.pcbi.1012545

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