Article
N-glycosylation of the envelope glycoprotein I is essential for the proliferation and virulence of the duck plague virus
26 Oct 2024
Abstract excerpt
Abstract Duck plague virus (DPV) causes the highly pathogenic duck plague, and the envelope glycoprotein I (gI), as one of the key virulence genes, has not yet had its critical virulence sites identified through screening. This study used reverse genetics technology to target the gI, specifically within the DPV genome. Four DPV mutants with gI N-glycosylation site mutations were designed and constructed, and...
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