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Evaluation of the Safety and Immunogenicity of Duck-Plague Virus gE Mutants

20 Apr 2022

Abstract excerpt

Duck plague (DP) is an acute infectious disease in the duck industry. The duck plague virus (DPV) is the pathogen, a subfamily of alphaherpesvirinae . gE is a type I membrane protein that contains three parts: an extracellular domain, a transmembrane domain, and a cytoplasmic domain. gE is the major virulence determinant of α-herpesvirus. However, the functions of the gE extracellular and cytoplasmic domains have...

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PMID: 35515004
DOI: 10.3389/fimmu.2022.882796

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