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Article

Envelope Protein Glycosylation Mediates Zika Virus Pathogenesis

29 Mar 2019

Abstract excerpt

It is unclear why the ability of Zika virus (ZIKV) to cause serious disease, including Guillain-Barré syndrome and birth defects, was not recognized until recent outbreaks. One contributing factor could be genetic differences between contemporary ZIKV strains and historical ZIKV strains. All isolates from recent outbreaks encode a viral envelope protein that is glycosylated, whereas many historical ZIKV strains...

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PMID: 30944176
DOI: 10.1128/jvi.00113-19

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