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Article

The association between aberrant salience and psychotic experiences in general population twins, and genetic vulnerability as a modifier.

BMC psychiatry - 26 Oct 2024

Drukker Marjan, Todor Tatvan, Bongaarts Jelle, Broggi Eleonora, Kelkar Mihika, Wigglesworth Thomas, Verhiel Kayle, van Leeuwen Karel, Koster Meinte, Derom Catherine, Thiery Evert, De Hert Marc, Menne-Lothmann Claudia, Decoster Jeroen, Collip Dina, van Winkel Ruud, Jacobs Nele, Guloksuz Sinan, Rutten Bart, van Os Jim

Abstract excerpt

BACKGROUND: Previous studies assessing the hypothesis that the construct of 'aberrant salience' is associated with psychosis and psychotic symptoms showed conflicting results. For this reason, the association between measures to index aberrant salience and subclinical psychotic symptoms in a general population sample was analysed. In addition, genetic vulnerability was added to the analysis as a modifier to test...

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Identifiers

PMID: 39462331
DOI: 10.1186/s12888-024-06176-2
PMCID: PMC11515186

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