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Patterns of HIV-1 Drug Resistance Observed Through Geospatial Analysis of Routine Diagnostic Testing in KwaZulu-Natal, South Africa.

Viruses - 19 Oct 2024

Gounder Lilishia, Khan Aabida, Manasa Justen, Lessells Richard, Tomita Andrew, Pillay Melendhran, Manyana Sontaga C, Govender Subitha, Francois Kerri-Lee, Moodley Pravi, Msomi Nokukhanya, Govender Kerusha, Parboosing Raveen, Moyo Sikhulile, Naidoo Kogieleum, Chimukangara Benjamin

Abstract excerpt

HIV-1 drug resistance (HIVDR) impedes treatment and control of HIV-1, especially in high-prevalence settings such as KwaZulu-Natal (KZN) province, South Africa. This study merged routine HIV-1 genotypic resistance test (GRT) data with Geographic Information Systems coordinates to assess patterns and geographic distribution of HIVDR in KZN, among ART-experienced adults with virological failure. We curated 3133 GRT...

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PMID: 39459966
DOI: 10.3390/v16101634
PMCID: PMC11512327

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