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A single-stranded based library preparation method for virome characterization

24 Oct 2024

Abstract excerpt

BACKGROUND: The gut virome is an integral component of the gut microbiome, playing a crucial role in maintaining gut health. However, accurately depicting the entire gut virome is challenging due to the inherent diversity of genome types (dsDNA, ssDNA, dsRNA, and ssRNA) and topologies (linear, circular, or fragments), with subsequently biases associated with current sequencing library preparation methods. To...

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PMID: 39449043
DOI: 10.1186/s40168-024-01935-5

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