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Efficient Recovery of Complete Gut Viral Genomes by Combined Short‐ and Long‐Read Sequencing

19 Jan 2024

Abstract excerpt

Current metagenome assembled human gut phage catalogs contained mostly fragmented genomes. Here, comprehensive gut virome detection procedure is developed involving virus-like particle (VLP) enrichment from ≈500 g feces and combined sequencing of short- and long-read. Applied to 135 samples, a Chinese Gut Virome Catalog (CHGV) is assembled consisting of 21,499 non-redundant viral operational taxonomic units...

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PMID: 38240578
DOI: 10.1002/advs.202305818

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