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Disulfidptosis-related subtype and prognostic signature in prostate cancer

23 Oct 2024

Abstract excerpt

BACKGROUND: Disulfidptosis refers to cell death caused by the accumulation and bonding of disulfide in the cytoskeleton protein of SLC7A11-high level cells under glucose deprivation. However, the role of disulfidptosis-related genes (DRGs) in prostate cancer (PCa) classification and regulation of the tumor microenvironment remains unclear. METHODS: Firstly, we analyzed the expression and mutation landscape of...

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PMID: 39444006
DOI: 10.1186/s13062-024-00544-4

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