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Article

RPN1: a pan-cancer biomarker and disulfidptosis regulator

1 May 2024

Abstract excerpt

Background: Elevated expression of SLC7A11, in conjunction with glucose deprivation, has revealed disulfidptosis as an emerging cell death modality. However, the prevalence of disulfidptosis across tumor cell lines, irrespective of SLC7A11 levels, remains uncertain. Additionally, deletion of the ribophorin I (RPN1) gene imparts resistance to disulfidptosis, yet the precise mechanism linking RPN1 to disulfidptosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38881923
DOI: 10.21037/tcr-24-581

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