Article
Monitoring for PERV Following Xenotransplantation
7 Oct 2024
Abstract excerpt
Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs. PERV-A, PERV-B and PERV-C can be released as infectious virus particles and PERV-A and PERV-B can infect human cells in culture. PERV-C does not infect human cells, but high-titer recombinant PERV-A/C can infect them. Retroviruses are able to induce immunosuppression and/or tumors in the infected host. Numerous methods have been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
