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Article

Causal and mediating effects of lipid and facial aging: association study integrating GWAS, eQTL, mQTL, and pQTL data.

Lipids in health and disease - 21 Oct 2024

Zhao Mingjian, He Zhanchen, Liu Lukuan, Wang Yichen, Gao LinQi, Shang Yuxuan, Zhu Mengru

Abstract excerpt

BACKGROUND: Increasing evidence suggests a potential causal association between lipid levels and facial aging. The aim of this study was to investigate the relationship between levels of specific lipids and facial aging via Mendelian randomization methods. Additionally, this study aimed to identify mediators and explore relevant genes and drug targets. METHODS: In this study, genome-wide association data on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39434152
DOI: 10.1186/s12944-024-02328-1
PMCID: PMC11492622

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