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Article

Biological aging accelerates hepatic fibrosis: Insights from the NHANES 2017-2020 and genome-wide association study analysis.

Annals of hepatology - 1 Jan 2025

Zhao Jiaxin, Zhou Huiying, Wu Rui, Ruan Chen, Wang Cheng, Ding Jiawei, Zhang Tao, Fang Zheyu, Zheng Huilin, Zhang Lei, Zhou Jie, Hu Zhenhua

Abstract excerpt

INTRODUCTION AND OBJECTIVES: This study aimed to investigate the association between biological aging and liver fibrosis in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). MATERIALS AND METHODS: We analyzed NHANES 2017-2020 data to calculate phenotypic age. Hepatic steatosis and fibrosis were identified using controlled attenuation parameters (CAP), fatty liver index (FLI) and...

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PMID: 39426601
DOI: 10.1016/j.aohep.2024.101579

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APOLD1

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