Article
Expanding the VEXAS diagnostic workup: the role of peripheral blood cytological analysis.
Frontiers in immunology - 1 Jan 2024
Baggio Chiara, Oliviero Francesca, Padoan Roberto, Iorio Luca, Bixio Riccardo, Orsolini Giovanni, Bertoldo Eugenia, Bernardi Cristina, Colavito Davide, Paiero Barbara, Pregnolato Giovanna, Ramonda Roberta, Doria Andrea, Bindoli Sara, Sfriso Paolo
Abstract excerpt
VEXAS syndrome is a newly described autoinflammatory entity characterized by somatic mutations in the UBA1 X-linked gene in hematopoietic progenitor cells. Several studies have demonstrated that the presence of vacuoles in progenitor cells from bone marrow aspirates is a hallmark finding for this syndrome. Therefore, this study aimed to characterize leukocytes from VEXAS patients versus patients with...
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