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Article

Impact of Leptin-Melanocortin Pathway Genetic Variants on Weight Loss Outcomes After Endoscopic Transoral Outlet Reduction.

Obesity surgery - 1 Nov 2024

Gala Khushboo, Ghusn Wissam, Fansa Sima, Anazco Diego, Storm Andrew C, Abu Dayyeh Barham K, Acosta Andres

Abstract excerpt

PURPOSE: Variants in the leptin-melanocortin pathway (LMP) are associated with severe obesity. We evaluated weight loss of patients with or without heterozygous LMP variants, with weight recurrence after Roux-en-Y gastric bypass, who underwent endoscopic transoral outlet reduction (TORe). MATERIALS AND METHODS: We retrospectively reviewed patients genotyped for an LMP who had undergone TORe, classified as...

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PMID: 39419959
DOI: 10.1007/s11695-024-07547-0

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