Article
Investigation of parasite genetic variation and systemic immune responses in patients presenting with different clinical presentations of cutaneous leishmaniasis caused by Leishmania aethiopica.
Infectious diseases of poverty - 16 Oct 2024
Yizengaw Endalew, Takele Yegnasew, Franssen Susanne, Gashaw Bizuayehu, Yimer Mulat, Adem Emebet, Nibret Endalkachew, Yismaw Gizachew, Cruz Cervera Edward, Ejigu Kefale, Tamiru Dessalegn, Munshea Abaineh, Müller Ingrid, Weller Richard, Cotton James A, Kropf Pascale
Abstract excerpt
BACKGROUND: Cutaneous leishmaniasis (CL) is a neglected tropical skin disease, caused by the protozoan parasite Leishmania. In Ethiopia, CL is mainly caused by Leishmania aethiopica and can present in different clinical forms. The aim of this study was to assess whether these different forms are associated with differences in parasite genetic and host systemic immune signatures. METHODS: Here we analysed the...
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