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Article

Genetic association of gut microbiota with osteoarthritis: a multivariable Mendelian randomization study considering medication use.

Journal of medical microbiology - 1 Oct 2024

Huang Ming-Hui, Liu Cai-Xia, Huang Yi-Sheng, He Ting-Yu, Dong Zi-Qiang

Abstract excerpt

Background. The interplay among human gut microbiota (GM) composition, osteoarthritis (OA) and OA-related medication use has been extensively discussed. However, to date, there has been no exploration of the genetic correlation among these three factors.Hypothesis/Gap. The potential causal link between GM and OA), and whether medications influence this relationship, remains unclear.Methods. We utilized...

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PMID: 39412235
DOI: 10.1099/jmm.0.001920

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