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Article

Abortive infection of bat fibroblasts with SARS-CoV-2

14 Oct 2024

Abstract excerpt

Bats are tolerant to highly pathogenic viruses such as Marburg, Ebola, and Nipah, suggesting the presence of a unique immune tolerance toward viral infection. Here, we compared severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection of human and bat ( Rhinolophus ferrumequinum ) pluripotent cells and fibroblasts. Since bat cells do not express an angiotensin-converting enzyme 2 (ACE2) receptor that...

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Identifiers

PMID: 39401365
DOI: 10.1073/pnas.2406773121

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