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Bat pluripotent stem cells reveal unusual entanglement between host and viruses

21 Feb 2023

Abstract excerpt

Bats are distinctive among mammals due to their ability to fly, use laryngeal echolocation, and tolerate viruses. However, there are currently no reliable cellular models for studying bat biology or their response to viral infections. Here, we created induced pluripotent stem cells (iPSCs) from two species of bats: the wild greater horseshoe bat (Rhinolophus ferrumequinum) and the greater mouse-eared bat (Myotis...

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PMID: 36812912
DOI: 10.1016/j.cell.2023.01.011

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