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Species-Specific Molecular Barriers to SARS-CoV-2 Replication in Bat Cells

5 Jul 2022

Abstract excerpt

Bats are host ancestors of several viruses that cause serious disease in humans, as illustrated by the ongoing SARS-CoV-2 pandemic. Progress in investigating bat-virus interactions has been hampered by a limited number of available bat cellular models. We have generated primary cells and cell lines from several bat species that are relevant for coronavirus research. The various permissivities of the cells to...

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PMID: 35862713
DOI: 10.1128/jvi.00608-22

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