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Article

Sex hormones and risk of lung and colorectal cancers in women: a Mendelian randomization study.

Scientific reports - 12 Oct 2024

Denos Marion, Sun Yi-Qian, Brumpton Ben Michael, Li Yafang, Albanes Demetrius, Burnett-Hartman Andrea, Campbell Peter T, Küry Sébastien, Li Christopher I, White Emily, Samadder Jewel N, Jenkins Mark A, Mai Xiao-Mei

Abstract excerpt

The roles of sex hormones such as estradiol, testosterone, and sex hormone-binding globulin (SHBG) in the etiology of lung and colorectal cancers in women, among the most common cancers after breast cancer, are unclear. This Mendelian randomization (MR) study evaluated such potential causal associations in women of European ancestry. We used summary statistics data from genome-wide association studies on sex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39396092
DOI: 10.1038/s41598-024-75305-4
PMCID: PMC11470916

Genes

SHBG

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