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Reduced SPOCK1 expression inhibits non-small cell lung cancer cell proliferation and migration through Wnt/β-catenin signaling.

1 Feb 2018

Abstract excerpt

OBJECTIVE: Accumulating evidence suggests that SPARC/osteonectin, cwcv, and kazal-like domain proteoglycan 1 (SPOCK1) contributes to the initiation and progression of human cancers. However, little is known about the function mechanisms of SPOCK1 in non-small cell lung cancer (NSCLC). The aim of this study was to investigate the molecular mechanism of SPOCK1 in NSCLC. PATIENTS AND METHODS: The expression levels...

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PMID: 29461591
DOI: 10.26355/eurrev_201802_14288

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