Article
Prioritization of drug targets for thyroid cancer: a multi-omics Mendelian randomization study.
Endocrine - 1 Nov 2024
Sun Hong, Li Ling, Yan Jingchao, Huang Taomin
Abstract excerpt
OBJECTIVES: Recurrence or tumor metastasis and drug resistance remain the major challenge in the treatment of thyroid cancer. It is needed to identify novel drug targets for thyroid cancer. METHODS: Summary data-based Mendelian randomization (SMR) and colocalization analysis were performed to evaluate the associations between gene methylation, expression, protein levels with thyroid cancer. We additionally...
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