Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Population Pharmacokinetic Model of Intravenous Immunoglobulin in Patients Treated for Various Immune System Disorders.

Clinical therapeutics - 1 Dec 2024

Lee Jian Lynn, Mohamed Shah Noraida, Makmor-Bakry Mohd, Islahudin Farida, Alias Hamidah, Mohd Saffian Shamin

Abstract excerpt

PURPOSE: Intravenous immunoglobulin (IVIG) is used to treat various immune system disorders, but the factors influencing its disposition are not well understood. This study aimed to estimate the population pharmacokinetic parameters of IVIG and to investigate the effect of genetic polymorphism of the FCGRT gene encoding the neonatal Fc receptor (FcRn) and clinical variability on the pharmacokinetic properties of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Histocompatibility Antigens Class I
Share to Immune System Diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulins, Intravenous

Share to Malaysia

Share to Models, Biological

Share to Polymorphism, Genetic

Share to Receptors, Fc

Share to Young Adult

Source

Identifiers

PMID: 39366801
DOI: 10.1016/j.clinthera.2024.09.018

Genes

FCGRT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 22 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population Pharmacokinetic Model of Intravenous Immunoglobulin in Patients Treated for Various Immune System Disorders.PMID 39366801Read ↗

Population Pharmacokinetic Models for Tacrolimus in non-transplant patients: A Systematic ReviewSemantic proximity Read ↗

Population pharmacokinetic study of tacrolimus in pediatric patients with primary nephrotic syndrome: A comparison of linear and nonlinear Michaelis-Menten pharmacokinetic model.Semantic proximity Read ↗

Population Pharmacokinetics and Factors Influencing Trough Concentration of Voriconazole in Children with Hematological MalignanciesSemantic proximity Read ↗

Dose tailoring of tacrolimus based on a non-linear pharmacokinetic model in children with refractory nephrotic syndrome.Semantic proximity Read ↗

Pharmacokinetic characterization of rituximab in patients with glomerular diseasesSemantic proximity Read ↗

Population pharmacokinetic models of tacrolimus in paediatric solid organ transplant recipients: A systematic review.Semantic proximity Read ↗

Application of stochastic simulation-estimation approach to the optimization of Pharmacokinetic studies design in the context of paediatric extrapolation: A step toward better decision making for drug sponsors and regulatorsSemantic proximity Read ↗

Understanding Inter-Individual Variability in Monoclonal Antibody DispositionSemantic proximity Read ↗

Intravenous immunoglobulins--understanding properties and mechanisms.Semantic proximity Read ↗

Population PK/PD model of tacrolimus for exploring the relationship between accumulated exposure and quantitative scores in myasthenia gravis patients.Semantic proximity Read ↗

Pharmacokinetics of bosentan in routinely treated Japanese pediatric patients with pulmonary arterial hypertension.Semantic proximity Read ↗

Efficacy of intravenous gammaglobulin for immunoglobulin G subclass and/or antibody deficiency in adults.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.