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Generation of an induced pluripotent stem cell line from a patient carrying FBN1/c.6734 G > A mutation.

Stem cell research - 1 Aug 2021

Pan Ziwei, Wang Hongkun, Wang Hao, Liu Yong, Liang Ping

Abstract excerpt

Mutations in FBN1 (gene encodes the matrix protein fibrillin 1), are usually associated with Marfan syndrome (MS). This syndrome contains ocular, skeletal, cardiovascular, pulmonary, cutaneous and neurological abnormalities. Here, we introduced an induced pluripotent stem cell (iPSC) line from a patient who suffered from severe cardiovascular disease and carried a c.6734G > A mutation in FBN1. Dermal fibroblasts...

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PMID: 34298435
DOI: 10.1016/j.scr.2021.102459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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Generation of an induced pluripotent stem cell line from a patient carrying FBN1/c.6734 G > A mutation.PMID 34298435Read ↗

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