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Article

[Genetics of congenital lipodystrophies].

Annales d'endocrinologie - 1 Oct 2015

Buffet A, Lombes M, Caron P

Abstract excerpt

Congenital lipodystrophies are heterogeneous genetic diseases, leading to the loss of adipose tissue. This loss of adipose tissue can be generalized or partial, thus defining different phenotypes. These lipodystrophies have a major metabolic impact, secondary to lipotoxicity. This lipotoxicity is responsible for insulin resistance, dyslipidemia and hepatic steatosis. The severity of the metabolic impact...

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Share to Adipocytes
Share to Adipose Tissue
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein gamma Subunits

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Source

Identifiers

PMID: 26776286
DOI: 10.1016/S0003-4266(16)30002-6

Genes

BSCL2
LMNA
PPARG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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