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Investigating the uncertain causal link between gut microbiota and glaucoma: A genetic correlation and Mendelian randomisation study.

Clinical & experimental ophthalmology - 1 Dec 2024

Li Jiayong, Ma Xin, Zhuo Kaichen, He Yuxian, Lin Mingkai, Wang Wei, Guo Shicheng, Tang Chao, Zhang Xu, Gao Xinbo

Abstract excerpt

BACKGROUND: Glaucoma is the most common cause of irreversible blindness, and gut microbiota (GM) is associated with glaucoma. Whether this association represents a causal role remains unknown. This study aims to assess the potential association and causal link between GM and various forms of glaucoma, emphasising the need for cautious interpretation of the strength of these associations. METHODS: Employing a...

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PMID: 39327062
DOI: 10.1111/ceo.14440

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