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Article

Genetic Evidence for the Causal Relationship Between Gut Microbiota and Diabetic Kidney Disease: A Bidirectional, Two-Sample Mendelian Randomisation Study.

Journal of diabetes research - 1 Jan 2024

Zhang Yun, Zhao Lingyun, Jia Yifan, Zhang Xin, Han Yueying, Lu Ping, Yuan Huijuan

Abstract excerpt

Aims: According to the gut-kidney axis theory, gut microbiota (GM) has bidirectional crosstalk with the development of diabetic kidney disease (DKD). However, empirical results have been inconsistent, and the causal associations remain unclear. This study was aimed at exploring the causal relationship between GM and DKD as well as the glomerular filtration rate (GFR) and urinary albumin-to-creatinine ratio...

Topics

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Diabetes Mellitus, Type 1
Diabetes Mellitus, Type 2
Diabetic Nephropathies
Gastrointestinal Microbiome
Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Glomerular Filtration Rate

Mendelian Randomization Analysis

Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 39479291
DOI: 10.1155/2024/4545595
PMCID: PMC11524706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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