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Article

Virus Infection Induces Immune Gene Activation with CTCF-anchored Enhancers and Chromatin Interactions in Pig Genome.

Genomics, proteomics & bioinformatics - 3 Dec 2024

Cao Jianhua, Ren Ruimin, Li Xiaolong, Zhang Xiaoqian, Sun Yan, Tian Xiaohuan, Liu Ru, Liu Xiangdong, Ruan Yijun, Li Guoliang, Zhao Shuhong

Abstract excerpt

Chromatin organization is important for gene transcription in pig genome. However, its three-dimensional (3D) structure and dynamics are much less investigated than those in human. Here, we applied the long-read chromatin interaction analysis by paired-end tag sequencing (ChIA-PET) method to map the whole-genome chromatin interactions mediated by CCCTC-binding factor (CTCF) and RNA polymerase II (RNAPII) in...

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Identifiers

PMID: 39312688
DOI: 10.1093/gpbjnl/qzae062
PMCID: PMC11725346

Genes

CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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