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Deciphering the multidimensional impact of IGFBP1 expression on cancer prognosis, genetic alterations, and cellular functionality: A comprehensive Pan-cancer analysis

1 Sept 2024

Abstract excerpt

Objectives IGF-binding protein 1 ( IGFBP1 ) is a key regulator of insulin-like growth factors, impacting biological processes, including cancer progression and prognosis. Materials and methods This study investigates genetic alterations affecting IGFBP1 expression in tumors using data from The Cancer Genome Atlas (TCGA) PanCancer Atlas via cBioPortal. We analyzed samples from 32 cancer types for mutation sites,...

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PMID: 39309809
DOI: 10.1016/j.heliyon.2024.e37402

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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