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Article

RREB1 could act as an immunological and prognostic biomarker: From comprehensive analysis to osteosarcoma validation.

International immunopharmacology - 25 Dec 2024

Zhang Zhiming, Liu Binfeng, Mei Lin, Chen Ruiqi, Zhou Haoyang, Li Zhihong

Abstract excerpt

BACKGROUND: The Ras-responsive element binding protein 1 (RREB1) is a transcription factor involved in various biological processes. Notably, RREB1 plays a role in tumor immunity by regulating tumor-related gene expression, shaping the tumor microenvironment, and modulating immune checkpoints. Given these functions, RREB1 has emerged as a potential regulatory target in tumor immunotherapy. However, a...

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Bone Neoplasms
Databases, Genetic
Gene Expression Regulation, Neoplastic
Immunotherapy
Lymphocytes, Tumor-Infiltrating

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Microsatellite Instability

Tumor Microenvironment

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PMID: 39405927
DOI: 10.1016/j.intimp.2024.113312

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