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Article

Toward building a comprehensive human pan-genome: The SEN-GENOME project.

American journal of human genetics - 3 Oct 2024

Gaye Amadou, Sene Andrea Regina G, Gadji Macoura, Deme Alioune, Cisse Aynina, Ndiaye Rokhaya

Abstract excerpt

The human reference genome (GRCh38), primarily sourced from individuals of European descent, falls short in capturing the vast genetic diversity across global populations. Efforts to diversify the reference genome face challenges in accessibility and representation, exacerbating the scarcity of African genomic data crucial for studying diseases prevalent in these populations. Sherman et al. proposed constructing...

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Identifiers

PMID: 39305906
DOI: 10.1016/j.ajhg.2024.08.017
PMCID: PMC11480787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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