Article
Association between iron status, preeclampsia and gestational hypertension: A bidirectional two-sample Mendelian randomization study.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) - 1 Dec 2024
Li Pengsheng, Wang Haiyan, Chen Ting, Chen Gengdong, Zhou Zixing, Ye Shaoxin, Lin Dongxin, Fan Dazhi, Guo Xiaoling, Liu Zhengping
Abstract excerpt
BACKGROUND: Several recent observational studies have reported that iron overload during pregnancy is associated with preeclampsia (PE) and gestational hypertension (GH). However, the causal association between iron status, PE, and GH is still not clear. METHODS: We performed a two-sample Mendelian randomization (MR) study using the genome-wide association study (GWAS) summary statistics of iron status, included...
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