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Article

Levels of Natural Antibodies Before and After Immunoglobulin Replacement Treatment Affect the Clinical Phenotype in Common Variable Immunodeficiency.

Journal of clinical immunology - 21 Sept 2024

Sarrigeorgiou Ioannis, Tsinti Gerasimina, Kalala Fani, Germenis Anastasios, Speletas Matthaios, Lymberi Peggy

Abstract excerpt

Natural antibodies (NAbs) occurring in individuals without prior exposure to specific antigens, provide direct first barrier protection against pathogens, and exert immunoregulation thus actively contributing to the maintenance of immune homeostasis, controlling inflammatory processes and preventing autoimmunity. Common variable immunodeficiency (CVID) is a heterogeneous group of disorders characterized by a...

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Identifiers

PMID: 39305354
DOI: 10.1007/s10875-024-01805-7
PMCID: PMC11416378

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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