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Fecal Immunoglobulin Levels as a Modifier of the Gut Microbiome in Patients with Common Variable Immunodeficiency

24 Mar 2023

Abstract excerpt

OBJECTIVE: Common variable immunodeficiency (CVID) is the most common clinically relevant entity of inborn errors of immunity. In these patients, an altered gut microbiome composition with reduced diversity has been described. We sought to investigate the fecal immunoglobulin levels and their impact on the gut microflora in patients with CVID. METHODS: We analyzed the gut microbiome of 28 CVID patients and 42...

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PMID: 36961604
DOI: 10.1007/s10875-023-01469-9

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