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Diagnostic and Therapeutic Implications of a FUS :: TFCP2 Fusion and ALK Activation in a Metastatic Rhabdomyosarcoma

1 Sept 2024

Abstract excerpt

The identification of gene fusions in rare sarcoma subtypes can have diagnostic, prognostic, and therapeutic impacts for advanced cancer patients. Here, we present a case of a 31-year-old male with a lytic lesion of the left mandible initially diagnosed as an osteosarcoma but found to have a TFCP2 fusion and ALK alteration, redefining the diagnosis and providing rationale for a novel treatment strategy....

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PMID: 39302072
DOI: 10.1002/gcc.23259

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