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Downregulation of APN1 and ABCC2 mutation in Bt Cry1Ac-resistant Trichoplusia ni are genetically independent.

Applied and environmental microbiology - 23 Oct 2024

Cotto-Rivera Rey O, Joya Noelia, Hernández-Martínez Patricia, Ferré Juan, Wang Ping

Abstract excerpt

The resistance to the insecticidal protein Cry1Ac from the bacterium Bacillus thuringiensis (Bt) in the cabbage looper, Trichoplusia ni, has previously been identified to be associated with a frameshift mutation in the ABC transporter ABCC2 gene and with altered expression of the aminopeptidase N (APN) genes APN1 and APN6, shown as missing of the 110-kDa APN1 (phenotype APN1¯) in larval midgut brush border...

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Identifiers

PMID: 39291983
DOI: 10.1128/aem.00742-24
PMCID: PMC11497812

Genes

ABCC2

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