Article
Resistance to Bacillus thuringiensis Cry1Ac toxin requires mutations in two Plutella xylostella ATP-binding cassette transporter paralogs.
PLoS pathogens - 1 Aug 2020
Liu Zhaoxia, Fu Shu, Ma Xiaoli, Baxter Simon W, Vasseur Liette, Xiong Lei, Huang Yuping, Yang Guang, You Shijun, You Minsheng
Abstract excerpt
The diamondback moth, Plutella xylostella, is a cosmopolitan pest and the first species to develop field resistance to toxins from the gram-positive bacterium Bacillus thuringiensis (Bt). Although previous work has suggested that mutations of ATP-binding cassette transporter subfamily C2 (ABCC2) or C3 (ABCC3) genes can confer Cry1Ac resistance, here we reveal that P. xylostella requires combined mutations in both...
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