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Article

The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activity

16 Sept 2024

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Share to Autophagy in Disease and Therapy
Share to Lipid metabolism and biosynthesis
Share to Mitochondrial Function and Pathology

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 39285229
DOI: 10.1038/s41388-024-03157-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

The tumor suppressor Parkin exerts anticancer effects through regulating mitochondrial GAPDH activityPMID 39285229Read ↗

Parkin exerts the tumor‐suppressive effect through targeting mitochondriaSemantic proximity Read ↗

Parkinson's disease-associated protein Parkin: an unusual player in cancer.Semantic proximity Read ↗

An emerging role of PARK2 in cancerSemantic proximity Read ↗

Parkin inhibits necroptosis to prevent cancerSemantic proximity Read ↗

Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathwaySemantic proximity Read ↗

p32 regulates mitochondrial morphology and dynamics through parkinSemantic proximity Read ↗

Bcl-2 Family Proteins Participate in Mitochondrial Quality Control by Regulating Parkin/PINK1-Dependent MitophagySemantic proximity Read ↗

Functions and characteristics of PINK1 and Parkin in cancerSemantic proximity Read ↗

Parkin inhibits BAK and BAX apoptotic function by distinct mechanisms during mitophagySemantic proximity Read ↗

Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis.Semantic proximity Read ↗

Somatic and germline mutations in the tumor suppressor gene PARK2 impair PINK1/Parkin-mediated mitophagy in lung cancer cellsSemantic proximity Read ↗

Parkin ubiquitinates mTOR to regulate mTORC1 activity under mitochondrial stressSemantic proximity Read ↗

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